Sen won his second round contest 21-17, 21-10, taking 72 minutes to complete the formality.
Expectations from the Indian male shuttlers will also be high, given their exploits in recent months.
Defending champion Lakshya Sen looked in fine fettle as he registered a straight-game win over compatriot H S Prannoy to make a winning start to his title defence at the Yonex-Sunrise India Open Super 750 badminton tournament, in Delhi, on Tuesday.
This was Satwik and Chirag's third loss this year against the world number 1 pair.
Sindhu and Saina will once again be India's best bet as they look to put up a good show this week.
World champion PV Sindhu made an early exit from the China Open but B Sai Praneeth kept the Indian flag fluttering with a hard-fought straight-game win to reach the men's singles quarter-finals.
A summary of sports events and sports persons, who made news on Sunday
While Saina made short work of USA's Beiwan Zhang, second seed Sindhu had to dig deep to get the better of Japanese Sayaka Sato.
The Indian men's doubles pair of Satwiksairaj Rankireddy and Chirag Shetty shocked reigning World champions Mohammad Ahsan and Hendra Setiawan to join P V Sindhu and Saina Nehwal in the quarter-finals of the US $750,000 French Open, in Paris, on Thursday.
World Championships bronze medallist Sen had earlier advanced to the men's singles semi-finals after his opponent Lu Guang Zu of China gave a walkover.
The Indian pair had participated in Super 1000 events in 2018 and 2019 but this is the first time it entered the semi-finals.
'When we are playing at our best, it's very difficult to beat us.'
Brimming with confidence, India will again look to punch above their weight when they run into 14-time winners Indonesia in the final of Thomas Cup in Bangkok on Sunday, seeking to create history one more time.
Now all eyes are on the two Super 1000 events -- Yonex Thailand Open (January 12-17) and Toyota Thailand Open (January 19-24) as the world's best return to action following a prolonged break.
Indian athletes, including the boxers and shooters, hit the ground running as they started their pre-Olympic training, hoping to live up to massive expectations in the pandemic-hit Games in Tokyo.
Saina Nehwal and reigning champion Sameer Verma were a step away from clinching the men's and women's singles titles respectively
Saina Nehwal guided the Indian women's team to a dominating 5-0 win over Germany to stay on course for a knockout berth in Uber Cup, but the men's team suffered a narrow 2-3 defeat against Hong Kong, staring at an early exit in Thomas Cup badminton tournament in Kunshan, China.
The eighth seeded Indian, who won the Indonesia Super Series Premier and Australian Super series Open in June, defeated Russia's Sergey Sirant 21-13 21-12 in less than 30 minutes. The World No. 8 will take on France's Lucas Corvee tomorrow.
Chirag said "it is difficult to stay motivated" in such uncertain times.
In hockey, the women's team continued its inspiring run with a silver medal at the Birmingham Commonwealth Games.
Summary of sports events and persons who made news on Tuesday.
Top shuttlers, including Saina Nehwal and Kidambi Srikanth, are likely to leave for Malaysia and Singapore via Doha to participate in the last two Olympic qualifiers next month due to travel bans imposed by the two countries in the wake of unprecedented spike in COVID-19 cases in India.
Star Indian shuttlers P V Sindhu and Kidambi Srikanth advanced to the Round of 16 after pulling off contrasting wins in the opening round of the US$ 700,000 Malaysia Open World Tour Super 750 tournament.
After losing the first game, the 24-year-old Indian rebounded strongly to clinch a 15-21, 21-13, 21-13 win over Wan Ho in a gruelling second-round clash that lasted almost an hour.
'They want us to win in every match, like in cricket.' 'It's so tough to play every tournament and win.'
Kashyap, a Commonwealth Games champion, was trailing 8-14 in the third game when he chose to retire after pulling his calf muscle.
India's badminton doubles specialist N Sikki Reddy on Saturday heaved a sigh of relief after returning negative for COVID-19 barely two days after testing positive for the contagious disease, saying she was "shocked" by the not-so-kind reactions her initial result attracted.
Indian contingent has an opportunity to go deep in the draw and recapture the trophy which has been won by just two Indians so far -- the legendary Prakash Padukone (1980) and P Gopichand (2001).
Top shuttler B Sai Praneeth and doubles player Dhruv Rawat have already pulled out after testing positive in the pre-departure testing.
P V Sindhu will be eager to return to the podium as former winner Saina Nehwal looks to regain her touch
India has huge expectations from these champions. Rediff.com's Laxmi Negi and Norma Godinho glance at their chances at the 2018 Commonwealth Games.
Summary of sports events and persons who made news on Tuesday
The Badminton World Federastion (BWF) unveiled a revised international calendar to salvage the remainder of the season, disrupted by the COVID-19 pandemic.
Earlier, the women's doubles pair of Ashwini Ponnappa and N Sikki Reddy suffered their second successive loss in the event, going down fighting 19-21, 20-22 to Bulgaria's Gabriela Stoeva and Stefani Stoeva to bow out of contention.
Jwala says Sindhu should scan through all the videos of her past matches and work on her strategy.
India on Sunday dethroned defending champions and 14-time winners Indonesia
Olympic silver medallist P V Sindhu advanced to the pre-quarterfinals of the women's singles competition after defeating Korea's Kim Hyo Min in the second round of the World Championship in Glasgow on Tuesday.
Gopichand, who shaped Sindhu and Olympic bronze-medallist Saina Nehwal among others, believes it will take some time for the next big star to emerge.
Star shuttler Kidambi Srikanth was disappointed after being called for a series of what he termed "ridiculous" service faults during his pre-quarterfinal match against China's Huang Yuxiang at the All England Championship.
A look at the historic achievements by India's athletes in 2022.